1.Identification
1.1 GHS Product identifier
| Product name | tetrachloromethane |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | tert-butyl N-acetate |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | For industry use only. Volatile organic compounds |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
1.5 Emergency phone number
| Emergency phone number | - |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 3
Acute toxicity - Dermal, Category 3
Acute toxicity - Inhalation, Category 3
Carcinogenicity, Category 2
Specific target organ toxicity – repeated exposure, Category 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
Hazardous to the ozone layer, Category 1
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |   |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H301 Toxic if swallowed H311 Toxic in contact with skin H331 Toxic if inhaled H351 Suspected of causing cancer H372 Causes damage to organs through prolonged or repeated exposure H412 Harmful to aquatic life with long lasting effects H420 Harms public health and the environment by destroying ozone in the upper atmosphere |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P273 Avoid release to the environment. |
| Response | P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/… P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P312 Call a POISON CENTER/doctor/…if you feel unwell. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P311 Call a POISON CENTER/doctor/… P308+P313 IF exposed or concerned: Get medical advice/ attention. P314 Get medical advice/attention if you feel unwell. |
| Storage | P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed. |
| Disposal | P501 Dispose of contents/container to ... P502 Refer to manufacturer or supplier for information on recovery or recycling |
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| tetrachloromethane | tetrachloromethane | 56-23-5 | none | 100% |
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
In case of skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Dizziness, incoordination, anesthesia; may be accompanied by nausea and liver damage. Kidney damage also occurs, often producing decrease or stopping of urinary output. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Irrigate eyes with water. Wash contaminated areas of body with soap and water. Gastric lavage, if swallowed, followed by saline catharsis. Oxygen and artificial respiration.
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
When fighting a fire in which carbon tetrachloride is involved, wear self-contained breathing apparatus.
5.2 Specific hazards arising from the chemical
Special Hazards of Combustion Products: Forms poisonous phosgene gas when exposed to open flames. Behavior in Fire: Decomposes to form chlorine and phosgene (USCG, 1999)
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
1. VENTILATE AREA OF SPILL OR LEAK. 2. COLLECT FOR RECLAMATION OR ABSORB IN VERMICULITE, DRY SAND, EARTH, OR A SIMILAR MATERIAL.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Separated from food and feedstuffs and metals. See Chemical Dangers. Ventilation along the floor. Cool.Store in a cool, dry, well-ventilated location. Separate from alkali metals.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
Recommended Exposure Limit: 60 Min Short-Term Exposure Limit: 2 ppm, 12.6 mg/cu m
NIOSH has recommended that carbon tetrachloride be treated as a potential human carcinogen.
NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concn.
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
| Physical state | clear colorless liquid |
|---|---|
| Colour | Colorless, clear, heavy liquid |
| Odour | SWEETISH, AROMATIC, MODERATELY STRONG ETHEREAL; SOMEWHAT RESEMBLING THAT OF CHLOROFORM |
| Melting point/ freezing point | -23oC |
| Boiling point or initial boiling point and boiling range | 76oC |
| Flammability | Noncombustible LiquidNot combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | Use any means suitable for fire extinguisher |
| Auto-ignition temperature | Not flammable (USCG, 1999) |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | 2.03X10-3 Pa.s @ 250.00 K |
| Solubility | In water:0.8 g/L (20 oC) |
| Partition coefficient n-octanol/water (log value) | log Kow= 2.83 |
| Vapour pressure | 4.05 psi ( 20 °C) |
| Density and/or relative density | 1.594 |
| Relative vapour density | 5.32 (vs air) |
| Particle characteristics | no data available |
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
... Generally inert ...
10.3 Possibility of hazardous reactions
Not flammableThe vapour is heavier than air.CARBON TETRACHLORIDE is a commonly used liquid in fire extinguishers to combat small fires. It has no flash point, it is not flammable. However, when heated to decomposition, it will emit fumes of extremely toxic phosgene and of hydrogen chloride. Forms explosive mixtures with chlorine trifluoride, calcium hypochlorite, decaborane, dinitrogen tetraoxide, fluorine. Forms impact-sensitive explosive mixtures with particles of many metals: lithium, sodium, potassium, beryllium, zinc, aluminum, barium. Vigorous exothermic reaction with allyl alcohol, boron trifluoride, diborane, disilane, aluminum chloride, dibenzoyl peroxide, potassium tert-butoxide, liquid oxygen, zirconium. [Bretherick, 5th ed., 1995, p. 666]. Potentially dangerous reaction with dimethylformamide or dimethylacetamide in presence of iron [Cardillo, P. et al., Ann. Chim. (Rome), 1984, 74, p. 129].
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
A paste of zinc powder and carbon tetrachloride (with kieselguhr as thickener) will readily burn after ignition by a high-temperature primer.
10.6 Hazardous decomposition products
Decomposes to form chlorine and phosgene.
11.Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 2920 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
NTP: Reasonably anticipated to be a human carcinogen
Reproductive toxicity
No information is available on the reproductive effects of carbon tetrachloride in humans. Limited epidemiological data have indicated a possible association between certain birth outcomes (e.g., birth weight, cleft palate) and drinking water exposure. However, as the water contained multiple chemicals, the role of carbon tetrachloride is unclear. Decreased fertility and degenerative changes in the testes have been observed in animals exposed to carbon tetrachloride by inhalation. Birth defects have not been observed in animals exposed to carbon tetrachloride by inhalation or ingestion.
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
- Toxicity to fish: LC50 Lepomis macrochirus (Bluegill) 125,000 ug/l/96 hr (static unmeasured)
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: The static screening flask test method measured >87% degradation of carbon tetrachloride in 7 days in the original test, and 100% degradation in the second, third, and fourth trials(1). In a standard dilution test, 0% Theoretical BOD for carbon tetrachloride was measured(2).
12.3 Bioaccumulative potential
A BCF of 3.2-7.4 for carbon tetrachloride was measured(1). A measured BCF value for trout, rainbow trout and bluegill sunfish was found to be 17.37(2,3), 52.48(5), and 30.2(4) and 26.3(5), respectively. According to a classification scheme(6), these BCF values suggest the potential for bioconcentration in aquatic organisms is low.
12.4 Mobility in soil
The Koc for carbon tetrachloride was measured to be 71(1). According to a classification scheme(4), this Koc value suggests that carbon tetrachloride is expected to have high mobility in soil. Estimated retardation factor in breakthrough sampling in groundwater - 1.44-1.8(2,3).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information
14.1 UN Number
| ADR/RID: UN1846 | IMDG: UN1846 | IATA: UN1846 |
14.2 UN Proper Shipping Name
| ADR/RID: CARBON TETRACHLORIDE |
| IMDG: CARBON TETRACHLORIDE |
| IATA: CARBON TETRACHLORIDE |
14.3 Transport hazard class(es)
| ADR/RID: 6.1 | IMDG: 6.1 | IATA: 6.1 |
14.4 Packing group, if applicable
| ADR/RID: II | IMDG: II | IATA: II |
14.5 Environmental hazards
| ADR/RID: no | IMDG: no | IATA: no |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| tetrachloromethane | tetrachloromethane | 56-23-5 | none |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
16.Other information
Information on revision
| Creation Date | Aug 17, 2017 |
|---|---|
| Revision Date | Aug 17, 2017 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/