1.Identification
1.1 GHS Product identifier
| Product name | dieldrin |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | (1aR,2R,2aS,3S,6R,6aR,7S,7aS)-rel-3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphth[2,3-b]oxirene |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | For industry use only. Pesticides (chemicals used for killing pests, such as rodents, insects, or plants) |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
1.5 Emergency phone number
| Emergency phone number | - |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 3
Acute toxicity - Dermal, Category 1
Carcinogenicity, Category 2
Specific target organ toxicity – repeated exposure, Category 1
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |    |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H301 Toxic if swallowed H310 Fatal in contact with skin H351 Suspected of causing cancer H372 Causes damage to organs through prolonged or repeated exposure H410 Very toxic to aquatic life with long lasting effects |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P273 Avoid release to the environment. |
| Response | P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/… P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P310 Immediately call a POISON CENTER/doctor/… P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P308+P313 IF exposed or concerned: Get medical advice/ attention. P314 Get medical advice/attention if you feel unwell. P391 Collect spillage. |
| Storage | P405 Store locked up. |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| dieldrin | dieldrin | 60-57-1 | none | 100% |
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest. Refer for medical attention.
In case of skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Give a slurry of activated charcoal in water to drink. Do NOT induce vomiting. Rest. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Inhalation, ingestion, or skin contact causes irritability, convulsions and/or coma, nausea, vomiting, headache, fainting, tremors. Contact with eyes causes irritation. (USCG, 1999)
This material is extremely toxic. It is rapidly absorbed through the skin. Symptoms appear between 20 minutes and 12 hours after exposure. There is evidence that this material may cause chromosomal damage. Doses of 1 mg/kg can cause symptoms. It is a suspected carcinogen. Also, it is a central nervous system depressant and hepatotoxin. Pregnant women are considered to be at special risk. (EPA, 1998)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Treatment is symptomatic and supportive. Oils should not be used as either cathartics or dermal cleansing agents, as they increase absorption. Gastric lavage and use of activated charcoal and sodium sulfate are indicated for ingestion. If dermal exposure occurred, contaminated clothes should be removed, and the skin should be thoroughly cleansed with soap and water. Management of seizures in both children and adults is with Valium or phenobarbital. Respiratory depression and even respiratory arrest especially with concomitant use of Valium and phenobarbital in children, may occur. These drugs preferably should be used only in critical care areas where emergency endotracheal intubation can be performed. ... Epinephrine can not be utilized in patients with organochlorine poisoning, as the organochlorines induce myocardial irritability and ventricular arrhythmias may occur. However, dopamine may be necessary in the event of hypotension unresponsive to fluid administration, and epinephrine may be necessary in the event of cardiopulmonary arrest. ... In a critically ill patient with unknown insecticide exposure, a trial of atropine and pralidoxime should not be withheld until the etiologic agent is discovered, for the use of these agents may prove life-saving in organophosphate poisoning. Atropine must be used with caution, as it can cause ventricular irritability, especially when a myocardial irritant such as an organochlorine is present. ... Hematologic, hepatic (especially with endrin, which is markedly hepatotoxic), and renal studies as well as cardiopulmonary monitoring should be carried out in acute intoxication from lindane or other organochlorines for at least 48 to 72 hr. Long term hematologic follow-up is necessary for the patient with lindane intoxication. As the carrier for these agents may be xylene or a petroleum distillate, management also must include observation and treatment for these entities. /Organochlorine pesticides/
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)
5.2 Specific hazards arising from the chemical
Special Hazards of Combustion Products: Toxic and irritating hydrogen chloride fumes may form in fire. (USCG, 1999)
Toxic hydrogen chloride and phosgene may be generated when solution burns. Avoid strong oxidizers, strong acids and parathion. (EPA, 1998)
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Do NOT wash away into sewer. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Personal protection: chemical protection suit including self-contained breathing apparatus.
6.3 Methods and materials for containment and cleaning up
Absorb spills with paper towels.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access.Storage temp: ambient; venting: open (flame arrester) (for liquid form)
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
NIOSH recommends that dieldrin be regulated as a potential human carcinogen.
NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concn.
Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 0.25 mg/cu m, skin
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
| Physical state | white or light brown powder or crystals |
|---|---|
| Colour | COLORLESS CRYSTALS |
| Odour | Mild, chemical odor. |
| Melting point/ freezing point | 143-144oC(lit.) |
| Boiling point or initial boiling point and boiling range | 385oC |
| Flammability | Noncombustible SolidNot combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | 155.314oC |
| Auto-ignition temperature | no data available |
| Decomposition temperature | 245°C |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | less than 1 mg/mL at 23.89°C |
| Partition coefficient n-octanol/water (log value) | log Kow= 5.40 |
| Vapour pressure | 3.1e-06 mm Hg at 20°C |
| Density and/or relative density | 1.849g/cm3 |
| Relative vapour density | 13.2 (vs air) |
| Particle characteristics | no data available |
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
STABLE TO LIGHT
10.3 Possibility of hazardous reactions
Not flammableDIELDRIN is sensitive to mineral acids, acid catalysts, acid oxidizing agents and active metals. It reacts with phenols. This compound is also slightly corrosive to metals. It may react vigorously with strong oxidizers such as chlorine and permanganates and strong acids such as sulfuric or nitric.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Strong oxidizers, active metals such as sodium, strong acids, phenols.
10.6 Hazardous decomposition products
When heated to decomposition, emits toxic fumes of /hydrogen chloride/.
11.Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 38.3 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group B2 Probable Human Carcinogen
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
- Toxicity to fish: LC50 Goldfish 37 ug/L/96 hr, bluegill sunfish 8 ug/L/96 hr, fathead minnow 16 ug/L/96 hr, rainbow trout 10 ug/L/96 hr, coho salmon 11 ug/L/96 hr, chinook 6 ug/L/96 hr, pumpkinseed 6.7 ug/L/96 hr, channel catfish 4.5 ug/L; LC50 Mosquito fish 8 ppb for 48 hr; LC50 Bluegill sunfish 170 ppb and fathead minnow 24 ppb for 24 hr.
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
Dieldrin was not biodegraded in standard screening tests using domestic wastewater during a 28 day incubation period(1) and is extremely persistent in soils(2) under both aerobic and anaerobic conditions(3). It took 7 yr for half of the dieldrin to disappear from soil field plots(4). No biodegradation in river waters has been noted(5,7). There is some evidence that microorganisms can form photodieldrin from dieldrin(4,6). Dieldrin, present at 100 mg/l, reached 0 percent of its theoretical BOD in 2.5 weeks using an activated sludge inoculum at 30 mg/l and the Japanese MITI test(8).
12.3 Bioaccumulative potential
BCF values of 4,860 to 14,500 were measured for carp exposed to 1 ug/l of dieldrin and BCF values of 5,390 to 12,500 were measured for carp exposed to 0.1 ug/l over a 10 week incubation period(1). A BCF value of 10,000 was reported for dieldrin in unspecified species of fish(2). A BCF value of 3,300 was reported for dieldrin in lake trout(3). According to a classification scheme(4), this BCF data suggests bioconcentration in aquatic organisms is very high(SRC).
12.4 Mobility in soil
An average Koc value of 8,370 was determined for dieldrin in 7 soils(1). Koc values of 9,722 (organic top soil), 1,957 (creek sediment) and 23,310 (sandy loam) were determined for dieldrin(2). Dieldrin has a measured log Koc of 3.87(3) and an Rf value for soil thin layer chromatography of 0.00(3,5). According to a classification scheme(6), these measured Koc values suggest that dieldrin is expected to have low to no mobility in soil(SRC). Even with high temperatures and prolonged leaching dieldrin was shown to be immobile(4).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information
14.1 UN Number
| ADR/RID: UN2811 | IMDG: UN2811 | IATA: UN2811 |
14.2 UN Proper Shipping Name
| ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. |
| IMDG: TOXIC SOLID, ORGANIC, N.O.S. |
| IATA: TOXIC SOLID, ORGANIC, N.O.S. |
14.3 Transport hazard class(es)
| ADR/RID: 6.1 | IMDG: 6.1 | IATA: 6.1 |
14.4 Packing group, if applicable
| ADR/RID: I | IMDG: I | IATA: I |
14.5 Environmental hazards
| ADR/RID: yes | IMDG: yes | IATA: yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| dieldrin | dieldrin | 60-57-1 | none |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Not Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Not Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Not Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
16.Other information
Information on revision
| Creation Date | Aug 18, 2017 |
|---|---|
| Revision Date | Aug 18, 2017 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/