Lornoxicam, a thienothiazine-derived monocarboxylic acid amide, holds significant importance as a nonsteroidal anti-inflammatory drug (NSAID) with potent analgesic properties. Its pharmacological mechanism involves the inhibition of prostaglandin synthesis through cyclo-oxygenase (COX) inhibition, making it effective in alleviating pain associated with inflammatory conditions, osteoarthritis, surgery, sciatica, and other inflammatory disorders. Metabolized primarily by the CYP2C9 enzyme in the liver, lornoxicam's pharmacokinetics are influenced by genetic polymorphisms and liver diseases such as cirrhosis. Physiologically based pharmacokinetic (PBPK) modeling has been employed to explore dosing strategies for different CYP2C9 genotypes and cirrhosis severity, enabling personalized dosing regimens. Additionally, machine learning techniques such as Support Vector Regression (SVR) have been utilized to model lornoxicam's solubility in supercritical solvents, providing valuable insights for drug formulation and dosage determination. Furthermore, studies on the inclusion of lornoxicam into mesoporous materials have demonstrated enhanced drug release profiles and improved bioavailability, offering a promising avenue for pharmaceutical applications.
There are many suppliers of Lornoxicam on the LookChem platform, such as HENAN NEW BLUE CHEMICAL CO.,LTD, HANGZHOU YUNUO CHEMICAL CO.,LTD, Dayang Chem (Hangzhou) Co.,Ltd.. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: Lornoxicam CAS number 70374-39-9 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of Lornoxicam price information you can contact us to purchase, if you need to purchase Lornoxicam in bulk, please send an inquiry message to get the latest prices and offers.
Name | CAS | Size | Price(USD) |
MACKLIN | 70374-39-9 | 5.00g | 57.76 |
MACKLIN | 70374-39-9 | 1.00g | 18.96 |
MACKLIN | 70374-39-9 | 25.00g | 251.34 |
Acmec | 70374-39-9 | 25.00g | 208.81 |
Acmec | 70374-39-9 | 5.00g | 50.60 |
Acmec | 70374-39-9 | 1.00g | 16.27 |
Picasso-e | 70374-39-9 | 25.00g | 528.51 |
Picasso-e | 70374-39-9 | 250.00mg | 21.34 |
Picasso-e | 70374-39-9 | 100.00mg | 12.54 |
Picasso-e | 70374-39-9 | 5.00g | 119.40 |
Picasso-e | 70374-39-9 | 1.00g | 40.15 |
Boer | 70374-39-9 | 1.00G | 131.34 |
Boer | 70374-39-9 | 5.00G | 395.52 |
Boer | 70374-39-9 | 1.00g | 18.21 |
Boer | 70374-39-9 | 5.00g | 55.52 |
Psaitong | 70374-39-9 | 1.00g | 17.61 |
Psaitong | 70374-39-9 | 5.00g | 72.99 |
MAYA | 70374-39-9 | 100.00MG | 29.85 |
MAYA | 70374-39-9 | 1.00G | 44.78 |
MAYA | 70374-39-9 | 1.00G | 10.45 |
MAYA | 70374-39-9 | 250.00MG | 7.46 |