基本信息
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羧芐青霉素鈉; 羧芐西林鈉; [6S-(2a,5a,6b)]-6-(羧基苯基-乙酰氨基)-3,3-二甲基-7-氧代-4-硫雜-1-氮雜雙環[3.2.0]庚烷-2-甲酸二鈉鹽
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4800-94-6
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Carbenicillin disodium salt; Disodium [2S-(2alpha,5alpha,6beta)]-6-(carboxylatophenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
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C17H18N2O6S.2Na
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422.36
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4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)-
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225-360-8
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4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-; Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-,disodium salt (7CI,8CI); Anabactyl; BRL 2064; CP 15639-2; Carbapen; Carbecin;Carbenicillin disodium; Carbenicillin disodium salt; Carbenicillin sodium;Carbenicilline disodium; Carboxybenzylpenicillin sodium; Disodium (a-carboxybenzyl)penicillin;Disodium carbenicillin; Fugacillin; Geocillin; Geopen; Gripenin; Hyoper;Microcillin; NSC 111071; Piopen; Pyopen; Pyopene; Sodium carbenicillin; a-Carboxybenzylpenicillin disodiumsalt; a-Carboxybenzylpenicillin sodiumsalt
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400oC
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737.8oC at 760 mmHg
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1、急性毒性:大鼠口經LD50: >10 gm/kg;大鼠腹腔LD50: 10 gm/kg;大鼠皮下LD50:>10 gm/kg 大鼠靜脈LD50:6800mg/kg;小鼠口徑LD50:>12 gm/kg;小鼠腹腔LD50:7600mg/kg 小鼠皮下LD50:9 gm/kg ;小鼠靜脈LD50:4500mg/kg;小鼠大腦內LD50:95500 ug/kg
詳細信息
其他名稱:羧芐西林鈉;[6S-(2a,5a,6b)]-6-(羧基苯基-乙酰氨基)-3,3-二甲基-7-氧代-4-硫雜-1-氮雜雙環[3.2.0]庚烷-2-甲酸二鈉鹽
CAS號:4800-94-6
C17H16N2Na2O6S=422.36
級別:USP級
效價:≥750mcg/mg
PH:6.5~8.0
水分:≤6.0%
性狀:白色或類白色結晶性粉末,易溶于水,能溶于甲醇,微溶于乙醇,幾乎不溶于苯或乙醚。有強吸濕性,對熱不穩定,有微臭,味苦
用途:生化研究。廣譜半合成青霉素。依靠在細菌細胞膜的內層面使轉肽酶(transpeptidases)失活抑制細菌細胞壁的合成。類似于青霉素。抗菌譜: 革蘭氏陰性和陽性細菌, 假單胞菌屬。
保存:2~8℃