基本信息
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四環素
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60-54-8
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四環素堿;
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C22H24N2O8
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444.43
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2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4S,4aS,5aS,6S,12aS)-
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200-481-9
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1.644g/cm3
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2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-(7CI,8CI); 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,[4S-(4a,4aa,5aa,6b,12aa)]-; (-)-Tetracycline; 4: PN: CN101531718 claimedsequence; Abramycin; Achromycin; Achromycin (naphthacene derivative);Acromicina; Actisite; Agromicina; Akne-Pyodron; Akne-Pyodron Kur; Ambramicina;Ambramycin; Apo-Tetra; Arcanacycline; Bio-Tetra; Biocycline; Britaciclina;Calociclina; Ciclibion; Cyclomycin; Cytome; Deschlorobiomycin; Dispatetrin;Economycin; Enterocycline; Florocycline; Gammatet; Ibicyn; Kinciclina; Latycin;Limecycline; Medocycline; Mericycline; Micycline; NSC 108579; Neocycline;NorTet; Novo-Tetra; Nu-Tetra; Omegamycin; Orlycycline; Panmycin; Polycycline;Polycycline (antibiotic); Quimocyclin N; Quimpe Antibiotico; Resteclin; Retet;Robitet Robicaps; Roviciclina; Sagittacin N; Servitet; Spaciclina; Steclin V;Sumycin syrup; Tetra Hubber; Tetra-Co; Tetra-Proter; Tetrabioptal; Tetracap;Tetracitro S; Tetracycline; Tetradecin; Tetrafil; Tetrafosammina; Tetralan;Tetralen; Tetramig; Tetramykoin; Tetraseptine; Triphacycline; Veracin;Vetacyclinum
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431.953oC
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175-177°C(lit.)
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790.622oC at 760 mmHg
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詳細信息
四環素
CAS NO.60-54-8
外觀:黃色結晶性粉末,有引濕性,遇光易變色。在堿性條件下易破壞失效。
臨床用途:四環素為廣譜抗生素,對多數革蘭氏陽性菌(如肺炎球菌,溶血性鏈球菌,部分葡萄球菌,炭疽桿菌、破傷風桿菌、梭狀芽孢桿菌等)和革蘭氏陰性菌(如大腸桿菌、流感桿菌、百日咳桿菌等)均有抗菌作用,此外還可抑制立克次體氏和支原體、衣原體等。四環素作用機制為干擾蛋白質的合成,臨床上主要用于肺炎、敗血癥、斑疹傷寒、淋巴肉芽腫、砂眼及其它細菌性感染等,亦可用于阿米巴痢疾和陰道滴蟲患者。
貯藏:密封或嚴封,遮光在干燥處保存。
質量標準:USP/部頒89版標準
包裝規格:25公斤/桶、25公斤/袋