中文名稱： D-色氨酸

中文別名： D-2-氨基-3-吲哚基丙酸; H-D-Trp-OH; D-(+)-色氨酸

英文名稱： D-(+)-Tryptophan

英文別名： D-Tryptophan; (R)-2-Amino-3-(3-indolyl)propionic acid; H-D-Trp-OH; 3-(2,3-dihydro-1H-indol-3-yl)-D-alanine

CAS號： 153-94-6

EINECS號： 205-819-9

分子式： C11H12N2O2

分子量： 204.23

InChI： InChI:1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)

分子結構：

密度： 1.232g/cm3

熔點： 282-285℃

沸點： 399.4°C at 760 mmHg

閃點： 195.4°C

水溶性： 11 g/L (20℃)

蒸汽壓： 4.27E-07mmHg at 25°C

物化性質：

熔點 282-285℃

比旋光度 31.5° (c=1, H2O 24℃)

水溶性 11 g/L (20℃)

產品用途：

是重要的營養劑，醫藥上用作癩皮病的防治劑

D-色氨酸(英文D(+)-Tryptophan)在常溫下為白色或類白色至微黃色的結晶性粉末，無臭或微臭，味稍甜。水中溶解度1.14克(25℃)，可溶于稀酸和稀堿，在堿中安穩，強酸中分化，微溶于乙醇，不溶于氯仿、乙醚，對人和動物的成長發育、推陳出新起重要的效果，被稱為第二必需氨基酸 ，與L-型的物理化學性質幾乎完全相同，僅旋光性相反，但它們的散布、功用及輔酶具有多樣性，熔點很高，一般在200度以上，能溶于水，在 近紫外光區域有吸收光的才能。

D-色氨酸特性與效果：D-色氨酸作為一種非蛋白活性氨基酸，具有特別的生理學性質，在食物飼料工業以及農業中能夠作為非養分甜味劑、飼料添加劑、植物成長劑 ，在醫藥行業中，首要用于組成各種多肽，替代L-色氨酸延伸肽類藥物的半衰期并下降副效果，不致發作抗藥性而成為酶按捺劑的重要組成前 體。能進步機體的免疫才能，推遲過敏性反應的發作。大多數多肽類抗生素能抗革蘭氏陽性菌，也有的對革蘭氏陰性菌如綠膿桿菌、分枝桿菌 、真菌、病菌、病菌和腫瘤細胞等有較好的按捺或殺滅效果。

用D-色氨酸組成半組成抗生素，其側鏈關于其藥理功用起著重要的效果，肽鍵很難被β-內酰酶效果，然后有較高的安穩性，并且有抗菌譜廣， 毒性小，過敏性低，吸收快，血濃度高，藥力繼續時間長等。

English name ： D-(+)-Tryptophan

English alias ： D-Tryptophan; (R)-2-Amino-3-(3-indolyl)propionic acid; H-D-Trp-OH; 3-(2,3-dihydro-1H-indol-3-yl)-D-alanine

CAS： 153-94-6

EINECS： 205-819-9

Molecular： C11H12N2O2

Molecular weight ： 204.23

InChI： InChI:1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)

Molecular structure ： D-(+)-Tryptophan 153-94-6

Density： 1.232g/cm3

Melting point： 282-285℃

Boiling point： 399.4°C at 760 mmHg

Flash point： 195.4°C

Water soluble： 11 g/L (20℃)

Steam pressure： 4.27E-07mmHg at 25°C

Ratio of spin 31.5° (c=1, H2O 24℃)

Water soluble 11 g/L (20℃)

Product use ：

Is an important nutrient. M

edically used as a prevention treatment agent fspitdisease

D-tryptophan (English D(-Tryptophan) crystalline powder white white-like to slightly yellow at room temperature，No odslight odor, slightly sweeter taste。Dissolved 1.14 g (25 degrees C) in water，Soluble in dilute acids alkalis，Stable in alkali, differentiation in strong acid, slightly soluble in ethanol, insoluble in chloroform、Ether，Important effecton on the growth development of humans animals，known as the second essential amino acid ，Almost identical to the physical chemical properties of the L-type，Only the opposite of the spin，But their dispersion, function, coenzyme are diverse.Melting point is very high, generally in more than 200 degrees, soluble in water, in the near ultraviolet light area has the ability to absorb light.

D-tryptophanacteristics effects:D-tryptophan, as a non-proteinactive amino acid, has a special physiological properties.Can be used as a non-nutrient sweetener, feed additive, plant growth agent in the food feed industry agriculture .In the pharmaceutical industry, the primary use is to form a variety of peptides，Substitute L-tryptophan extended peptide drugs with half-life decreased side effects，The precursof enzyme-pressing agent without anti-drug resistance.Can improve the body's immune ability, delay the onset of allergic reactions。Most peptide antibiotics are resistant to gram-positive bacteria, some have vegmy-negative bacteria such as chlorella, mycobacterium, fungi, germs, germs tumcells.Better press kill effect.

Semi-composed antibiotics made up of D-tryptophan，Its side chain plays an important role in its pharmacological function，Peptide bonds are difficult to be beta-containitolase effects，then there's a higher degree of stability.，there is a broad antibacterial spectrum, small toxicity, hypoallergenic, rapid absorption, high blood concentration, drug strength continues fa long time, etc.