Chemicals used in pharmaceutical research
Pioglitazone Hydrochloride is an orally-active thiazolidinedione with significant antidiabetic and potential antineoplastic properties. As an aromatic ether, it functions primarily by activating peroxisome proliferator-activated receptor gamma (PPARγ), influencing gene transcription related to insulin response, inhibiting cell growth, and promoting cell differentiation and angiogenesis. Despite its efficacy in treating Type-2 diabetes mellitus and improving insulin sensitivity, its clinical use is limited due to risks of congestive heart failure and bladder tumors. Pioglitazone Hydrochloride's poor aqueous solubility presents a challenge for therapeutic applications, categorized as Class II in the biopharmaceutics classification system. Recent research explores its co-encapsulation with chemotherapy agents like capecitabine to enhance anticancer efficacy, particularly in colorectal cancer treatment. Spectrophotometric methods have been developed for precise quantification in pharmaceutical formulations, ensuring quality control. Additionally, dietary supplementation studies in broiler chickens indicate pioglitazone's potential to improve growth performance and meat quality by modulating lipid metabolism and antioxidant gene expression. Preferential solvation studies reveal its solubility behavior in various solvent mixtures, crucial for optimizing its pharmaceutical formulations.
There are many suppliers of [5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride on the LookChem platform, such as Dayang Chem (Hangzhou) Co.,Ltd., Amadis Chemical Co., Ltd., HENAN NEW BLUE CHEMICAL CO.,LTD. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: [5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride CAS number 112529-15-4 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of [5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride price information you can contact us to purchase, if you need to purchase [5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride in bulk, please send an inquiry message to get the latest prices and offers.
| Name | CAS | Size | Price(USD) |
| MACKLIN | 112529-15-4 | 100.00g | 141.79 |
| MACKLIN | 112529-15-4 | 1.00g | 6.27 |
| MACKLIN | 112529-15-4 | 5.00g | 14.33 |
| MACKLIN | 112529-15-4 | 25.00g | 40.15 |
| Acmec | 112529-15-4 | 100.00mg | 41.49 |
| Acmec | 112529-15-4 | 25.00g | 37.76 |
| Acmec | 112529-15-4 | 100.00g | 134.33 |
| Acmec | 112529-15-4 | 10.00g | 24.78 |
| Acmec | 112529-15-4 | 5.00g | 12.54 |
| Acmec | 112529-15-4 | 1.00g | 6.42 |
| Picasso-e | 112529-15-4 | 100.00mg | 6.27 |
| Picasso-e | 112529-15-4 | 100.00g | 294.03 |
| Picasso-e | 112529-15-4 | 25.00g | 82.69 |
| Picasso-e | 112529-15-4 | 10.00g | 54.18 |
| Picasso-e | 112529-15-4 | 5.00g | 27.61 |
| Picasso-e | 112529-15-4 | 1.00g | 14.48 |
| Picasso-e | 112529-15-4 | 250.00mg | 9.40 |
| Picasso-e | 112529-15-4 | 100.00g | 167.76 |
| Picasso-e | 112529-15-4 | 10.00g | 27.91 |
| Picasso-e | 112529-15-4 | 250.00mg | 5.22 |
| Boer | 112529-15-4 | 1.00g | 5.97 |
| Boer | 112529-15-4 | 5.00g | 12.69 |
| Boer | 112529-15-4 | 25.00g | 38.51 |
| Boer | 112529-15-4 | 25.00G | 73.13 |
| Boer | 112529-15-4 | 5.00G | 20.90 |
| MAYA | 112529-15-4 | 25.00G | 19.40 |
| MAYA | 112529-15-4 | 5.00G | 5.97 |
| MAYA | 112529-15-4 | 1.00G | 14.93 |
| Psaitong | 112529-15-4 | 1.00g | 6.72 |
| Psaitong | 112529-15-4 | 5.00g | 12.54 |
| Psaitong | 112529-15-4 | 25.00g | 37.16 |