Chemicals used in the synthesis of pharmaceutical intermediates
Chemicals used in the development of organic light-emitting diodes (OLEDs)
Chemicals used to develop new polymers and plastics
Chemicals used in materials science
Chemicals used in organic synthesis
2-Cyano-4'-methylbiphenyl (OTBN) serves as a crucial intermediate compound in the synthesis of various pharmaceuticals, particularly sartans, which are essential nonpeptide angiotensin II antagonists. Traditionally, the commercial production of OTBN involves Wohl–Ziegler bromination from 2-cyano-4'-methylbiphenyl, relying on chlorinated solvents like chlorobenzene or carbon tetrachloride. However, the dependence on these troublesome solvents poses environmental and health hazards. Hence, there's a growing interest in identifying greener solvent alternatives. Through response surface methodology (RSM) coupled with solvent principal components analysis, solvents with suitable characteristics for this reaction have been identified. Carbonate esters, particularly propylene carbonate and diethyl carbonate, have emerged as promising replacements, exhibiting high conversion rates and yields. Additionally, the solubility, dissolution thermodynamic properties, and solid-liquid phase equilibrium of OTBN in various solvents and binary solvent mixtures have been extensively studied.
There are many suppliers of 4'-Methyl-2-cyanobiphenyl on the LookChem platform, such as Zibo Hangyu Biotechnology Development Co., Ltd, Dayang Chem (Hangzhou) Co.,Ltd., Hangzhou Dingyan Chem Co., Ltd. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: 4'-Methyl-2-cyanobiphenyl CAS number 114772-53-1 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of 4'-Methyl-2-cyanobiphenyl price information you can contact us to purchase, if you need to purchase 4'-Methyl-2-cyanobiphenyl in bulk, please send an inquiry message to get the latest prices and offers.
| Name | CAS | Size | Price(USD) |
| MACKLIN | 114772-53-1 | 500.00g | 34.33 |
| MACKLIN | 114772-53-1 | 100.00g | 9.85 |
| MACKLIN | 114772-53-1 | 25.00g | 4.48 |
| MACKLIN | 114772-53-1 | 5.00g | 4.33 |
| MACKLIN | 114772-53-1 | 2.50kg | 155.97 |
| Acmec | 114772-53-1 | 500.00g | 32.24 |
| Acmec | 114772-53-1 | 1.00kg | 64.03 |
| Acmec | 114772-53-1 | 25.00g | 3.88 |
| Acmec | 114772-53-1 | 100.00g | 6.87 |
| Picasso-e | 114772-53-1 | 500.00g | 70.60 |
| Picasso-e | 114772-53-1 | 100.00g | 15.07 |
| Picasso-e | 114772-53-1 | 25.00g | 8.51 |
| Picasso-e | 114772-53-1 | 5.00g | 4.48 |
| Picasso-e | 114772-53-1 | 1000.00g | 140.15 |
| Picasso-e | 114772-53-1 | 10.00g | 5.97 |
| RHAWN | 114772-53-1 | 5.00g | 4.33 |
| RHAWN | 114772-53-1 | 500.00g | 56.72 |
| RHAWN | 114772-53-1 | 25.00g | 7.46 |
| RHAWN | 114772-53-1 | 100.00g | 16.57 |
| ALADDIN | 114772-53-1 | 100.00g | 11.34 |
| ALADDIN | 114772-53-1 | 500.00g | 44.03 |
| ALADDIN | 114772-53-1 | 25.00g | 4.63 |
| ALADDIN | 114772-53-1 | 10.00g | 4.48 |
| ALADDIN | 114772-53-1 | 5.00g | 4.33 |
| Boer | 114772-53-1 | 10.00G | 37.31 |
| Boer | 114772-53-1 | 500.00g | 32.99 |
| Boer | 114772-53-1 | 25.00g | 4.33 |
| Boer | 114772-53-1 | 2.50kg | 138.06 |
| Boer | 114772-53-1 | 5.00g | 4.18 |
| Boer | 114772-53-1 | 100.00g | 9.40 |
| YUANYE | 114772-53-1 | 5.00g | 3.73 |
| Accela | 114772-53-1 | 500.00g | 50.57 |
| Accela | 114772-53-1 | 100.00g | 13.28 |
| Accela | 114772-53-1 | 25.00g | 4.63 |
| Accela | 114772-53-1 | 10.00g | 4.48 |