Chemicals used in antiviral therapy
Chemicals used to inhibit viral replication
Sofosbuvir, marketed under the brand name Sovaldi among others, is an oral medication primarily used to treat hepatitis C. It functions by inhibiting the RNA polymerase that the hepatitis C virus (HCV) uses to replicate. Sofosbuvir is often combined with other antiviral drugs, such as velpatasvir, forming a fixed-dose combination that is effective and safe for patients with chronic hepatitis C and end-stage renal disease, achieving a high sustained virological response (SVR) rate. Resistance to sofosbuvir can develop due to specific mutations in the HCV NS3/4A protease, impacting its efficacy. Additionally, advanced techniques like vibrational circular dichroism (VCD) spectroscopy have been employed to distinguish polymorphs and cocrystals of sofosbuvir, enhancing its pharmaceutical applications. Furthermore, sofosbuvir has been successfully used off-label to treat vaccine-associated yellow fever in an immunocompromised patient, showcasing its potential beyond hepatitis C treatment.
There are many suppliers of Sofosbuvir on the LookChem platform, such as CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD, HANWAYS CHEMPHARM CO.,LIMITED, Hubei Vanz Pharm Co.,Ltd. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: Sofosbuvir CAS number 1190307-88-0 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of Sofosbuvir price information you can contact us to purchase, if you need to purchase Sofosbuvir in bulk, please send an inquiry message to get the latest prices and offers.
| Name | CAS | Size | Price(USD) |
| MACKLIN | 1190307-88-0 | 5.00mg | 4.78 |
| MACKLIN | 1190307-88-0 | 25.00mg | 14.93 |
| MACKLIN | 1190307-88-0 | 100.00mg | 48.51 |
| Acmec | 1190307-88-0 | 1.00g | 67.01 |
| Acmec | 1190307-88-0 | 5.00g | 223.73 |
| Acmec | 1190307-88-0 | 250.00mg | 22.24 |
| ALADDIN | 1190307-88-0 | 5.00MG | 4.33 |
| Boer | 1190307-88-0 | 5.00mg | 4.78 |
| Boer | 1190307-88-0 | 25.00mg | 14.63 |
| Boer | 1190307-88-0 | 100.00mg | 47.61 |
| Psaitong | 1190307-88-0 | 10.00mg | 52.24 |
| Psaitong | 1190307-88-0 | 100.00mg | 135.82 |
| Psaitong | 1190307-88-0 | 50.00mg | 90.30 |