Agomelatine, a melatonergic agonist and 5-HT2C antagonist, is primarily used as an antidepressant with beneficial effects on sleep and fewer discontinuation and sexual side effects compared to other antidepressants. It has shown efficacy in treating sleep and mood disorders in epilepsy patients, providing greater improvement in anxiety and sleep quality over escitalopram without significant adverse events. Additionally, agomelatine demonstrates solubility variations in different solvents, with its solvation thermodynamics and intermolecular interactions influencing its dissolution behavior. Beyond its antidepressant uses, agomelatine has potential anti-inflammatory properties, effectively inhibiting TNFα-induced NF-κB activation and inflammatory cytokine production in vitro and showing therapeutic benefits in a collagen-induced arthritis mouse model by targeting inducible nitric oxide synthase (iNOS) and modulating the iNOS/ERK/p65 signaling pathway.
There are many suppliers of Agomelatine on the LookChem platform, such as Zibo Hangyu Biotechnology Development Co., Ltd, Wuhan Wonda Pharm Limited, Xi'an Yinherb Bio-Tech Co., Ltd.. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: Agomelatine CAS number 138112-76-2 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of Agomelatine price information you can contact us to purchase, if you need to purchase Agomelatine in bulk, please send an inquiry message to get the latest prices and offers.
| Name | CAS | Size | Price(USD) |
| MACKLIN | 138112-76-2 | 25.00g | 181.79 |
| MACKLIN | 138112-76-2 | 1.00g | 13.88 |
| MACKLIN | 138112-76-2 | 250.00mg | 9.70 |
| MACKLIN | 138112-76-2 | 100.00g | 567.16 |
| MACKLIN | 138112-76-2 | 5.00g | 52.54 |
| MACKLIN | 138112-76-2 | 25.00mg | 5.97 |
| MACKLIN | 138112-76-2 | 5.00mg | 4.33 |
| Acmec | 138112-76-2 | 1.00g | 13.58 |
| Acmec | 138112-76-2 | 250.00mg | 14.33 |
| Acmec | 138112-76-2 | 5.00mg | 83.58 |
| RHAWN | 138112-76-2 | 5.00mg | 4.18 |
| Boer | 138112-76-2 | 1.00G | 207.46 |
| Boer | 138112-76-2 | 5.00mg | 4.18 |
| Boer | 138112-76-2 | 5.00g | 50.45 |
| Boer | 138112-76-2 | 1.00g | 13.28 |
| Boer | 138112-76-2 | 25.00mg | 5.67 |
| Boer | 138112-76-2 | 250.00mg | 9.25 |
| Boer | 138112-76-2 | 25.00g | 188.81 |
| Psaitong | 138112-76-2 | 25.00g | 178.96 |
| Psaitong | 138112-76-2 | 5.00g | 50.60 |
| Psaitong | 138112-76-2 | 1.00g | 13.28 |