Chemicals used in clinical research
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Chemicals used in cancer treatment
Bortezomib, a proteasome inhibitor, exhibits multifaceted effects in the treatment of multiple myeloma (MM). In MM cells, bortezomib inhibits proliferation and induces autophagy, partly through TFEB-mediated mechanisms, with potential downstream involvement of the MAPK pathway. Additionally, bortezomib sensitivity in MM is influenced by the expression of the chemokine receptor CCR1, with high CCR1 expression associated with decreased responsiveness to bortezomib treatment. Furthermore, bortezomib enhances TRAIL-mediated cytotoxicity in resistant rhabdomyosarcoma (RMS) tumors by upregulating the TRAIL receptor DR5, particularly when combined with ErbB2 (Her2)-targeted CAR-NK-92 cells.
There are many suppliers of Bortezomib on the LookChem platform, such as Hangzhou Think Chemical Co. Ltd, ACHIEVER SYSTEAM BIOCHEM CO., LTD., Hangzhou Dingyan Chem Co., Ltd. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: Bortezomib CAS number 179324-69-7 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of Bortezomib price information you can contact us to purchase, if you need to purchase Bortezomib in bulk, please send an inquiry message to get the latest prices and offers.
| Name | CAS | Size | Price(USD) |
| MACKLIN | 179324-69-7 | 1.00g | 159.70 |
| MACKLIN | 179324-69-7 | 500.00mg | 93.28 |
| MACKLIN | 179324-69-7 | 100.00mg | 30.60 |
| MACKLIN | 179324-69-7 | 25.00mg | 14.48 |
| MACKLIN | 179324-69-7 | 5.00g | 597.01 |
| Acmec | 179324-69-7 | 5.00mg | 56.42 |
| Acmec | 179324-69-7 | 5.00g | 598.81 |
| Acmec | 179324-69-7 | 1.00g | 156.57 |
| Acmec | 179324-69-7 | 250.00mg | 50.15 |
| Acmec | 179324-69-7 | 100.00mg | 29.10 |
| Picasso-e | 179324-69-7 | 250.00mg | 109.70 |
| Picasso-e | 179324-69-7 | 5.00g | 658.21 |
| Picasso-e | 179324-69-7 | 50.00mg | 37.61 |
| Picasso-e | 179324-69-7 | 1.00g | 219.40 |
| Picasso-e | 179324-69-7 | 100.00mg | 63.58 |
| Picasso-e | 179324-69-7 | 25.00mg | 14.63 |
| ALADDIN | 179324-69-7 | 5.00MG | 5.82 |
| Boer | 179324-69-7 | 50.00MG | 132.84 |
| Boer | 179324-69-7 | 10.00MG | 43.28 |
| Boer | 179324-69-7 | 1.00g | 164.48 |
| Boer | 179324-69-7 | 25.00mg | 14.03 |
| Boer | 179324-69-7 | 500.00mg | 100.0 |
| Boer | 179324-69-7 | 100.00mg | 30.30 |
| Psaitong | 179324-69-7 | 1.00g | 147.76 |
| Psaitong | 179324-69-7 | 100.00mg | 28.36 |
| Psaitong | 179324-69-7 | 250.00mg | 101.49 |