Dapagliflozin, marketed as Farxiga and Forxiga, is a medication primarily used for treating type 2 diabetes but has also shown promise in managing other conditions such as heart failure and chronic kidney disease. Studies have explored its efficacy and safety in various contexts, including its use in patients with acute heart failure (AHF). While dapagliflozin initiation during AHF hospitalization did not significantly reduce weight-based diuretic efficiency, it was associated with enhanced diuresis, reduced loop diuretic doses, and expedited hospital discharge. Additionally, dapagliflozin has emerged as a potential game-changer in the therapeutic landscape of type 2 diabetes mellitus (T2DM). As an SGLT-2 inhibitor, dapagliflozin acts independently of the insulin pathway by inhibiting glucose reuptake in renal tubules, resulting in glycosuria and decreased blood glucose levels. With its once-daily dosing and favorable safety profile, dapagliflozin has the potential to become a central therapy for T2DM and associated cardiovascular and renal complications. Furthermore, dapagliflozin has shown promising antipyroptotic effects in preventing kidney podocyte pyroptosis via modulation of the miR-155-5p/HO-1/NLRP3 axis in diabetic nephropathy, suggesting its potential as a therapeutic option for pyroptosis-related kidney damage in diabetes.
There are many suppliers of Dapagliflozin on the LookChem platform, such as Tianjin Kind Pharma Co., Ltd., Shandong Hanjiang Chemical Co., Ltd., Luhan Pharmachem Co., Ltd. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: Dapagliflozin CAS number 461432-26-8 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of Dapagliflozin price information you can contact us to purchase, if you need to purchase Dapagliflozin in bulk, please send an inquiry message to get the latest prices and offers.
| Name | CAS | Size | Price(USD) |
| MACKLIN | 461432-26-8 | 100.00g | 2238.81 |
| MACKLIN | 461432-26-8 | 25.00g | 673.43 |
| MACKLIN | 461432-26-8 | 200.00mg | 22.09 |
| MACKLIN | 461432-26-8 | 5.00g | 204.33 |
| MACKLIN | 461432-26-8 | 1.00g | 70.90 |
| Acmec | 461432-26-8 | 25.00g | 672.54 |
| Acmec | 461432-26-8 | 250.00mg | 26.12 |
| Acmec | 461432-26-8 | 10.00g | 348.21 |
| Acmec | 461432-26-8 | 100.00mg | 18.36 |
| Acmec | 461432-26-8 | 5.00g | 196.72 |
| Acmec | 461432-26-8 | 1.00g | 68.36 |
| Acmec | 461432-26-8 | 20.00mg | 84.78 |
| Boer | 461432-26-8 | 1.00g | 69.70 |
| Boer | 461432-26-8 | 200.00mg | 21.19 |
| Boer | 461432-26-8 | 5.00g | 200.30 |
| Psaitong | 461432-26-8 | 250.00mg | 21.64 |
| Psaitong | 461432-26-8 | 1.00g | 26.87 |
| Psaitong | 461432-26-8 | 25.00g | 679.10 |
| Psaitong | 461432-26-8 | 5.00g | 200.75 |
| Psaitong | 461432-26-8 | 1.00g | 72.39 |
| Psaitong | 461432-26-8 | 250.00mg | 21.64 |
| Psaitong | 461432-26-8 | 25.00g | 679.10 |
| Psaitong | 461432-26-8 | 5.00g | 195.37 |