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Glutamine is a nonessential/conditionally essential amino acid that plays a pivotal role in clinical illness and stress conditions. Glutamine (Gln) has pleiotropic roles in cellular metabolism. For example, the carbon skeleton of Gln contributes to the tricarboxylic acid (TCA) cycle intermediates. This process is mediated by glutaminase (GLS), which converts Gln into glutamate (Glu). Gln-derived Glu is further converted into α-ketoglutarate (AKG) by the activity of Glu dehydrogenase or by transaminase activity (for example, aspartate transaminase, glutamate oxaloacetate transaminase 1 (GOT1) and GOT2). AKG is further used to generate other TCA cycle intermediates, lipids and reducing equivalents. The amide nitrogen of Gln supplies nitrogen for the biosynthesis of several metabolites, including amino acids, hexosamines and nucleotides. Glutamine in cancer cells plays critical and diverse roles by providing not only a source of nitrogen for amino acid and nucleotide biosynthesis but also a source of carbon to replenish the tricarboxylic acid (TCA) cycle and lipid biosynthesis pathways; thus, cancer cells are “addicted” to glutamine. Glutamine metabolism and closely linked metabolic networks involving glutamine transporters, glutaminase, aminotransferase, and redox homeostasis are essential for cancer cell survival. Targeting each step of glutamine metabolism has shown promising results in cancer treatment, prompting the discovery of druggable targets and the development of anticancer drug candidates. In addition, given that immune checkpoint inhibitors are now widely used to treat cancer, the role of glutamine blockade within the tumor microenvironment (TME) has gained much attention. Glutamine metabolism plays a central role in regulating uncontrolled tumor growth by modulating bioenergetic and redox homeostasis and by serving as a precursor for the synthesis of biomass.
There are many suppliers of L-Glutamine on the LookChem platform, such as HENAN NEW BLUE CHEMICAL CO.,LTD, Hangzhou Maytime Bio-Tech Co.,Ltd., ORCHID CHEMICAL SUPPLIES LTD. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: L-Glutamine CAS number 56-85-9 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of L-Glutamine price information you can contact us to purchase, if you need to purchase L-Glutamine in bulk, please send an inquiry message to get the latest prices and offers.
Name | CAS | Size | Price(USD) |
MACKLIN | 56-85-9 | 500.00g | 48.66 |
MACKLIN | 56-85-9 | 25.00g | 6.87 |
MACKLIN | 56-85-9 | 2.50kg | 140.30 |
MACKLIN | 56-85-9 | 500.00g | 32.09 |
MACKLIN | 56-85-9 | 100.00g | 17.31 |
MACKLIN | 56-85-9 | 100.00g | 11.49 |
MACKLIN | 56-85-9 | 2.50kg | 100.15 |
MACKLIN | 56-85-9 | 25.00g | 5.37 |
Acmec | 56-85-9 | 1.00g | 42.99 |
Acmec | 56-85-9 | 200.00mg | 13.13 |
Acmec | 56-85-9 | 25.00g | 3.88 |
Acmec | 56-85-9 | 1.00kg | 55.97 |
Acmec | 56-85-9 | 100.00g | 5.22 |
Acmec | 56-85-9 | 500.00g | 20.75 |
Picasso-e | 56-85-9 | 1000.00g | 87.16 |
Picasso-e | 56-85-9 | 500.00g | 43.88 |
Picasso-e | 56-85-9 | 100.00g | 11.34 |
Picasso-e | 56-85-9 | 25.00g | 6.57 |
RHAWN | 56-85-9 | 500.00g | 40.15 |
RHAWN | 56-85-9 | 500.00g | 74.63 |
RHAWN | 56-85-9 | 100.00g | 12.99 |
RHAWN | 56-85-9 | 25.00g | 6.27 |
ALADDIN | 56-85-9 | 250.00g | 28.51 |
ALADDIN | 56-85-9 | 25.00g | 6.57 |
ALADDIN | 56-85-9 | 100.00g | 13.28 |
ALADDIN | 56-85-9 | 2.50kg | 103.28 |
ALADDIN | 56-85-9 | 500.00g | 40.90 |
Boer | 56-85-9 | 500.00g | 37.91 |
Boer | 56-85-9 | 2.50kg | 135.52 |
Boer | 56-85-9 | 25.00g | 5.82 |
Boer | 56-85-9 | 100.00g | 12.39 |
Boer | 56-85-9 | 2.50kg | 157.46 |
Boer | 56-85-9 | 100.00g | 16.57 |
Boer | 56-85-9 | 500.00g | 46.72 |
Boer | 56-85-9 | 25.00g | 6.57 |
Boer | 56-85-9 | 100.00G | 68.66 |
Boer | 56-85-9 | 25.00G | 32.09 |
Psaitong | 56-85-9 | 2.50kg | 78.36 |
Psaitong | 56-85-9 | 100.00g | 11.94 |
Psaitong | 56-85-9 | 500.00g | 26.12 |
Psaitong | 56-85-9 | 25.00g | 3.73 |
Psaitong | 56-85-9 | 500.00g | 234.03 |
Psaitong | 56-85-9 | 25.00g | 19.85 |
Psaitong | 56-85-9 | 100.00g | 52.99 |
Psaitong | 56-85-9 | 1.00kg | 361.19 |
MAYA | 56-85-9 | 500.00G | 26.87 |
MAYA | 56-85-9 | 100.00G | 4.48 |
MAYA | 56-85-9 | 25.00G | 5.22 |
YUANYE | 56-85-9 | 200.00mg | 13.43 |
YUANYE | 56-85-9 | 25.00g | 4.48 |
YUANYE | 56-85-9 | 5.00g | 2.24 |
J&K | 56-85-9 | 500.00g | 57.61 |
J&K | 56-85-9 | 100.00g | 14.48 |
J&K | 56-85-9 | 100.00g | 20.90 |
J&K | 56-85-9 | 25.00g | 10.75 |
J&K | 56-85-9 | 500.00g | 46.27 |
J&K | 56-85-9 | 25.00g | 8.21 |
Accela | 56-85-9 | 500.00g | 41.49 |
Accela | 56-85-9 | 100.00g | 12.69 |
Accela | 56-85-9 | 25.00g | 6.12 |