Dasatinib hydrate is a pharmaceutical compound categorized as a tyrosine kinase inhibitor (TKI) primarily used in the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It exerts its therapeutic effects by selectively inhibiting multiple tyrosine kinases, including BCR-ABL, SRC family kinases, and c-KIT, which are implicated in the pathogenesis of these hematological malignancies. Dasatinib hydrate is typically administered orally in tablet form and is rapidly absorbed from the gastrointestinal tract, reaching peak plasma concentrations within a few hours. The addition of water molecules to the dasatinib molecule forms the hydrate form, which does not significantly alter its pharmacological activity. Common side effects of dasatinib hydrate include myelosuppression, fluid retention, gastrointestinal disturbances, and skin rash. Despite these adverse effects, dasatinib hydrate has demonstrated significant efficacy in inducing hematologic and cytogenetic responses in patients with CML and Ph+ ALL, making it a valuable therapeutic option in the management of these diseases.
There are many suppliers of Dasatinib monohydrate on the LookChem platform, such as Afine Chemicals Limited, Yangzhou Qinyuan Pharmatech Co.,Ltd, Simagchem Corporation. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: Dasatinib monohydrate CAS number 863127-77-9 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of Dasatinib monohydrate price information you can contact us to purchase, if you need to purchase Dasatinib monohydrate in bulk, please send an inquiry message to get the latest prices and offers.
| Name | CAS | Size | Price(USD) |
| MACKLIN | 863127-77-9 | 100.00mg | 8.36 |
| MACKLIN | 863127-77-9 | 10.00g | 305.67 |
| MACKLIN | 863127-77-9 | 500.00mg | 29.55 |
| MACKLIN | 863127-77-9 | 2.00g | 77.01 |
| Acmec | 863127-77-9 | 500.00mg | 66.87 |
| Acmec | 863127-77-9 | 100.00mg | 13.13 |
| Acmec | 863127-77-9 | 1.00g | 56.57 |
| Acmec | 863127-77-9 | 5.00g | 178.96 |
| Acmec | 863127-77-9 | 250.00mg | 22.24 |
| Acmec | 863127-77-9 | 100.00mg | 14.78 |
| RHAWN | 863127-77-9 | 100.00mg | 15.52 |
| Boer | 863127-77-9 | 100.00mg | 8.81 |
| Boer | 863127-77-9 | 500.00mg | 38.21 |
| Boer | 863127-77-9 | 2.00g | 73.88 |
| Psaitong | 863127-77-9 | 1.00g | 40.30 |
| Psaitong | 863127-77-9 | 5.00g | 136.12 |
| Psaitong | 863127-77-9 | 250.00mg | 14.63 |
| J&K | 863127-77-9 | 250.00mg | 228.36 |
| J&K | 863127-77-9 | 50.00mg | 114.93 |