Chemicals used in clinical research
Chemicals used to inhibit tyrosine kinases
Chemicals used in targeted therapy
Chemicals used in cancer treatment
Crizotinib is a potent small-molecule tyrosine kinase inhibitor known for its efficacy in treating various cancers, particularly those characterized by specific genetic mutations. In non-small-cell lung cancer (NSCLC) with ROS1 rearrangement, Crizotinib has demonstrated marked antitumor activity, highlighting its effectiveness in targeting ROS1 proto-oncogene receptor tyrosine kinase. Additionally, Crizotinib has shown promise in the treatment of anaplastic lymphoma kinase (ALK)-positive lymphomas, particularly in cases where traditional chemotherapy has failed. Notably, Crizotinib has exhibited a high overall response rate in ALK-positive lymphoma patients, including those who have developed resistance to cytotoxic therapy. Furthermore, Crizotinib has displayed a unique mechanism in resensitizing cancers with specific resistance mutations, such as the L1198F mutation, which confers resistance to third-generation inhibitors but paradoxically enhances binding to Crizotinib, thus reinstating its efficacy.
There are many suppliers of Crizotinib on the LookChem platform, such as Zibo Hangyu Biotechnology Development Co., Ltd, Hangzhou Dingyan Chem Co., Ltd, Simagchem Corporation. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: Crizotinib CAS number 877399-52-5 with a purity of over 98% that needs to be transported to Los Angeles, USA.
Here are some small packages of Crizotinib price information you can contact us to purchase, if you need to purchase Crizotinib in bulk, please send an inquiry message to get the latest prices and offers.
| Name | CAS | Size | Price(USD) |
| MACKLIN | 877399-52-5 | 5.00g | 190.45 |
| MACKLIN | 877399-52-5 | 1.00g | 38.81 |
| MACKLIN | 877399-52-5 | 500.00mg | 22.69 |
| MACKLIN | 877399-52-5 | 100.00mg | 7.76 |
| MACKLIN | 877399-52-5 | 25.00g | 729.55 |
| Acmec | 877399-52-5 | 1.00g | 87.76 |
| Acmec | 877399-52-5 | 250.00mg | 31.04 |
| Boer | 877399-52-5 | 500.00mg | 21.79 |
| Boer | 877399-52-5 | 1.00g | 37.31 |
| Boer | 877399-52-5 | 100.00mg | 7.46 |
| Psaitong | 877399-52-5 | 5.00g | 188.06 |
| Psaitong | 877399-52-5 | 50.00mg | 11.94 |
| Psaitong | 877399-52-5 | 100.00mg | 17.91 |
| Psaitong | 877399-52-5 | 1.00g | 38.81 |